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Product lists

(Immobilized) enzymes (pdf)

Chiral intermediates (pdf)

Chiral intermediates (sdf)

 

 

 

Brochures                  

Immobilized hydrolase kit

Immobilized lipases kit

Immobilized proteases kit

 

 

 

Publications

 

CHEManager Europe, 06/2009, p 9.

"Immobilized Bulk Enzymes Catalysts for Chiral Intermediate and Chiral API Production"

 

Pharmachem, April/May 2009, p 10.

"Immobilized bulk proteases in enzymatic resolution. Production of non-natural amino acids with high chiral purity"

 

SP2, April 2007, p 26.

"Carrier-bound enzymes for chiral compound production".

 

Specialty Chemicals Magazine, October 2007, Vol 27, nr 8, p 38.

 "Industrial biocatalysis with standard hydrolytic bulk enzymes".

 

Chiral technology - enzymatic resolution
 

ChiralVision is the specialist in enzymatic resolution. By using only cheap hydrolytic bulk enzymes, enzyme costs per kilogram of end product can be kept to an absolute minimum. Furthermore, because the enzymes are freely available on the market a steady supply and the lowest possible price is guaranteed. The target for enantiomeric excess is >99%.

Successful approach

By using up to 75 different hydrolytic enzymes in combination with clever substrate derivatisation a very high success rate is achieved. No expensive designer enzyme is needed to get an enantiomeric excess of over 99%. In many cases racemisation of the unwanted isomer is possible. Subsequent recycling leads to a process with high yields.

Field of application

Almost any chiral compound is accessible via enzymatic resolution. It is particularly applicable for chiral:

  • alcohols and diols

  • amines

  • amides

  • a-amino acids  (also with multiple chiral centers)

  • b-amino acids

  • amino alcohols

  • acids

  • esters

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