A study based on 135 chiral centers in 69 chiral drug syntheses showed the most important sources of chirality are chiral pool (55%) and classical resolution (28%). Larger scale processes tend to move to chemo and / or biocatalytic methods, for reasons of cost-effectiveness.
Enzymes can replace traditional chemicals or additives and help to save water and energy in a variety of production processes. Enzymes are found in all living organisms - for API production always non-human and non-animal bacterial or plant enzymes are used.
ChiralVision is the specialist in route development comprising enzymatic conversions [chiral resolution, enantioselective synthesis and regio/chemoselective conversions]. We have an extended experience in process development and scale-up of enzymatically prepared chiral active pharmaceutical ingredients (API). We can help you to develop new and proprietary routes to generic APIs.
Relying on the strength of our knowledge base and scientific talent, ChiralVision has generated a steady stream of breakthroughs over the years resulting in many new patented API production methods.
The food industry utilizes a variety of enzymes for processing of foods. For example immobilized lipases can act on a variety of substrates including natural oils, synthetic triglycerides and esters of fatty acids.
The use of enzymatic technologies for removing contaminants from water provides a safe and economic alternative to commonly used physical-chemical treatment.
Enzymes can replace traditional chemicals or additives and help to save water and energy in a variety of production processes.
The market for industrial enzymes is to expand significantly with the cosmetics industry being one of the principle drivers.